Antimicrobial dressings – Mepilex® Ag

Antimicrobial foam dressing for acute and chronic wounds with signs of infection

Mepilex Ag is a foam dressing for medium exuding chronic or acute wounds like venous leg ulcers or burns, where an antimicrobial action is indicated.  According to a recent international experts consensus, antimicrobial action is indicated to help reduce bioburden in infected wounds and to act as an antimicrobial barrier in wounds at high risk of infection or re-infection1. Infected wounds are painful wounds that need the best of treatment. Mepilex Ag is a dressing with Safetac® technology, and therefore proven to minimize pain and skin damage at dressing changes2,3. Mepilex Ag is clinically proven to heal burns faster and with less pain and cost compared to silver sulfadiazine4.

Minimizes pain at dressing changes2,3

Rapid and sustained antimicrobial activity5,6,7,8

Gentle adherence, conformable and soft9,10

Does not slip under dressing retention and can be cut to size*

When to use Mepilex Ag



Mepilex Ag is designed for the management of low to moderately exuding wounds that show signs of infection. Mepilex Ag can be used under compression bandaging.

Mepilex Ag is a soft and highly conformable anti-microbial foam dressing that absorbs exudate and maintains a moist wound environment. The Safetac layer seals the wound edges, preventing the exudate from leaking onto the surrounding skin, thus minimizing the risk for maceration. The Safetac layer ensures that the dressing can be changed without damaging the wound or surrounding skin or exposing the patient to additional pain.

Mepilex Ag inactivates wound related pathogens within 30 minutes with sustained effect up to 7 days5,6,7,8. By reducing the number of microorganisms, Mepilex Ag may also reduce odour11

Use Mepilex Ag:

  • When an antimicrobial action is indicated: to reduce bioburden in infected wounds
  • When an antimicrobial action is indicated: to act as an antimicrobial barrier in wounds at high risk of infection or re-infection1
  • To obtain a rapid (after 30 minutes) and sustained (for 7 days) effective antimicrobial effect7,8
  • To combine antimicrobial action to a less painful and less stressful care for your patients1,12

Antimicrobial Foam Dressing with Safetac Technology

Mepilex® Ag combines the unique features of Safetac technology with the bacteria reducing power of silver. Mepilex Ag goes to work quickly, inactivating wound pathogens within 30 minutes and for up to 7 days. At dressing removal, Mepilex Ag does not stick to the wound or strip surrounding skin, minimizing patient pain and wound trauma.

Minimizing trauma and pain

Mepilex Ag hurts less by:

  • not adhering to the moist wound bed
  • eliminating skin stripping
  • sealing the wound margins to
  • prevent maceration

Reducing bacterial burden

Mepilex Ag in action:

  • inactivates wound pathogens within 30 minutes
  • inactivates wound pathogens up to 7 days
  • inactivates a broad range of pathogens, including MRSA

Exudate management and other benefits

Mepilex Ag features many more important benefits:

  • excellent conformability
  • good exudate management properties
  • can be cut to suit various wound sizes and difficult-to-dress areas


Mepilex® Ag is designed for the management of a wide range of wounds including leg ulcers, diabetic foot ulcers, pressure ulcers and partial thickness burns. Mepilex® Ag will effectively manage most exudate levels and can be used in conjunction with compression therapy.


  1. Gently cleanse the wound; dry surrounding skin. Mepilex® Ag will not adhere to a moist surface.
  2. Apply Mepilex® Ag directly onto the wound allowing the dressing to overlap onto the surrounding skin by at least 2 cm.
  3. Remove the release film and lay adherent side to the wound. Do not stretch. For lower limb applications position Mepilex® Ag slightly off centre so more of the dressing rests below the wound than above.
  4. Secure Mepilex® Ag in place with Mepitac®, Mefix® or other fixation device.

Mepilix Ag Application Guidelines


  • Do not use for patients with a known sensitivity to silver.
  • Do not use on patients undergoing radiation therapy
  • Do no use on patients undergoing MRI (Magnetic Resonance Imaging).
  • Do not use in conjunction with oxidizing agents such as hypochlorite solutions or hydrogen peroxide.

*microbes larger than 25nm


  • Mepilex® Ag should be used under the supervision of a qualified health care professional.
  • In the event of clinical infection Mepilex® Ag does not replace the need for systemic therapy or other adequate infection treatment.
  • The interaction of Mepilex® Ag with other topical treatments has not been demonstrated.
  • Other than saline solution or water, the interaction of cleansing agents in combination with Mepilex® Ag has not been demonstrated.
  • Mepilex® Ag may cause transient discoloration of the wound bed and surrounding skin.
Product no Size cm Pcs/box Pcs/case
287110 10 x 10 5 70
287210 10 x20 5 45
287310 15 x 15 5 25
287410 20 x 20 5 20
287510 20 x 50 2 12

Mepilex® Ag is packaged sterile in single packs

  1. International consensus. Appropriate use of silver dressings in wounds. An expert working group consensus. London: Wounds International, 2012.
  2. White R. A Multinational survey of the assessment of pain when removing dressings. Wounds UK, 2008.
  3. Dykes PJ et al. Effect of adhesive dressings on the stratum corneum of the skin. Journal of Wound Care, 2001.
  4. Silverstein et al. An open, parallel, randomized, comparative,multi-center investigation in the US evaluating the cost-effectiveness, efficacy, safety and tolerance of Mepilex® Ag versus Silvadene® in the treatment of partial thickness burns. Oral Presentation. The JAB Burn and Wound Care Symposium. Maui,Hawaii, USA, Feb 2010.
  5. Taherinejad and Hamberg. Antimicrobial effect of a silver-containing foam dressing on a broad range of common wound pathogens. Measured in vitro. Poster publication, WUWHS 2008.
  6. Hamberg K, Jakobsen C, Correlation of silver release and antimicrobial effect of silver-containing wound dressing in vitro, Poster presentation at EWMA Conference, Vienna, Austria, 2012.
  7. External test, NAMSA, Study no: 05C48747_01
  8. External test, NAMSA, Study no: 06_C60855_02 and 06_C60858_02
  9. Palomar F, Treatment and Care of chronic wounds and perilesional skin using a selfadhesive silicone and foam dressing. Spanish Congress of Dermatology nursing in Benalmádena (Málaga) March 2007.
  10. Young MJ, Robbie J Management of the diabetic foot: A guide to the assessment and management of diabetic foot ulcers, The Diabetic Foot, 2002 5(3)
  11. Barrett S. 2009 A review article examines the role of MepilexAg, the rapid and sustained antimicrobial action of silver with the benefits of Safetac technology.
  12. Upton D et al. The Impact of Atraumatic Vs Conventional Dressings on Pain and Stress in Patients with Chronic Wounds. Journal of Wound Care, 2012.

* Mepilex Ag does not need to be cut to the size of the wound when compression is used

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